Although this natural remedy still inspires controversy, there is increasing evidence that Glucosamine does in fact ease joint pain and inflammation for many arthritis sufferers, and that it may slow progression of the disease.

Because of its ability to ease the pain of osteoarthritis, some physicians and researchers feel Glucosamine might offer similar benefits for people suffering from rheumatoid arthritis, ankylosing spondylitis, spinal disc degeneration, tendinitis, bursitis, and physical injuries to the joints. There is even speculation that it could play a preemptive role, eliminating the development of osteoarthritis in people over 40.

What It Is; Why It Works

Glucosamine is a natural sugar produced by the body and found in certain foods. It plays an important role in the production, maintenance, and repair of cartilage, the white, smooth, rubber-like padding that covers the ends of bones and prevents them from rubbing against each other painfully as we move. It also helps form ligaments, tendons, and nails.

Glucosamine stimulates the production of glycosaminoglycans and proteoglycans, two essential building blocks of cartilage. In most cases, the joints produce sufficient Glucosamine to keep the cartilage in good repair, but if they fail to do so, it dries out, degenerates, cracks, and may even completely wear away. Left unprotected, the joints then become swollen, stiff, inflamed, tender, and painful--the condition known as osteoarthritis.

Advocates believe that by taking artificially synthesized Glucosamine sulfate supplements, osteoarthritis sufferers can "jump start" the natural production of Glucosamine by their own bodies. Combining Glucosamine with chondroitin sulfate is thought to increase its effectiveness.

While Glucosamine has been used to treat osteoarthritis in Europe since the 1980s, its use in the United States has been confined mainly to arthritic animals. However, several scientific studies have recently supported its effectiveness, and its popularity in this country is spreading quickly.

Avoid If...

No known medical conditions preclude the use of Glucosamine.

Special Cautions

Although Glucosamine may relieve your osteoarthritis, other treatments--such as a regular exercise program--remain just as important. If you have this condition, it's wise to keep in touch with your doctor for regular check-ups.

Unlike the potent nonsteroidal anti-inflammatory drugs (NSAIDs) usually prescribed for arthritis, Glucosamine does not produce serious side effects. You might, however, experience mild symptoms such as diarrhea, heartburn, indigestion, and nausea. Try taking the medication with food if it upsets your stomach (or if you have an ulcer). If this fails to eliminate the symptoms, check with your doctor.

Possible Drug Interactions

Glucosamine sulfate taken alone or in combination with chondroitin does not interfere with NSAIDs, aspirin, or any other anti-inflammatory or analgesic medication. Indeed, there is some evidence that taking this supplement may help people reduce their use of these strong drugs.

Liquid or Pill?

Recent research suggest, liquid glucosamine has much more efficacy than the powdered form found in pills. The reason? Better absorption leads to quicker and longer lasting relief. Also, filler often takes up a high percentage of pills.

A leading glucosamne supplement is Syn-Flex®. Syn-Flex® is a fast-acting, high-quality osteoarthritis supplement that works for humans and pets. Fomulated with pharmaceutical quality liquid glucosamine sulfate, glucosamine hydrochloride, chondroitin sulfate, and ten other arthritis-fighting ingredients, Syn-Flex® will ease your pain quickly. Learn more about Syn-Flex® here.